| Descriptor English: | Transcription Activator-Like Effector Nucleases | ||||||
| Descriptor Spanish: |
Nucleasas de los Efectores Tipo Activadores de la Transcripción
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| Descriptor Portuguese: | Nucleases dos Efetores Semelhantes a Ativadores de Transcrição | ||||||
| Descriptor French: | Nucléases effectrices de type activateur de transcription | ||||||
| Entry term(s): |
Nucleases, Transcription Activator Like Effector Nucleases, Transcription Activator-Like Effector TALEN TALENs Transcription Activator Like Effector Nucleases |
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| Tree number(s): |
D08.811.277.352.335.350.850 D12.776.828.300.850 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000069896 | ||||||
| Scope note: | Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.1.- | ||||||
| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56473 | ||||||
| Unique ID: | D000069896 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Transcription Activator-Like Effector Nucleases
- Preferred
| Concept UI |
M000608253 |
| Scope note | Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors. |
| Preferred term | Transcription Activator-Like Effector Nucleases |
| Entry term(s) |
Nucleases, Transcription Activator Like Effector Nucleases, Transcription Activator-Like Effector TALEN TALENs Transcription Activator Like Effector Nucleases |
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