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Descriptor English: Oxyphenbutazone
Descriptor Spanish: Oxifenilbutazona
Descriptor oxifenilbutazona
Entry term(s) hidroxifenilbutazona
Scope note: Fármaco antiinflamatorio no esteroideo. Se han utilizado colirios de oxifenbutazona en algunos lugares para el control de la inflamación ocular postoperatoria, heridas oculares superficiales y epiescleritis (AMA, Drug Evaluations Annual, 1994, p2000). Se ha utilizado, por vía oral, en trastornos reumáticos como la espondilitis anquilosante, osteoartritis y artritis reumatoide, pero ese uso ya no se considera justificado debido al riesgo de efectos secundarios hematológicos graves. (Martindale, The Extra Pharmacopoeia, 30th ed, p27)
Descriptor Portuguese: Oxifenilbutazona
Descriptor French: Oxyphenbutazone
Entry term(s): Diflamil
Hydroxyphenylbutazone
Oxyphenylbutazone
Tanderil
Tree number(s): D03.383.129.539.850.777.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010113
Scope note: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
Annotation: a non-steroidal anti-inflamm agent
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Inflammatory Agents, Non-Steroidal
Registry Number: H806S4B3NS
CAS Type 1 Name: 3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-
Public MeSH Note: 64
History Note: 64(63)
DeCS ID: 27753
Unique ID: D010113
NLM Classification: QV 95
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1964/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Oxyphenbutazone - Preferred
Concept UI M0015686
Scope note A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
Preferred term Oxyphenbutazone
Entry term(s) Hydroxyphenylbutazone
Oxyphenylbutazone
Diflamil - Narrower
Concept UI M0473943
Preferred term Diflamil
Tanderil - Narrower
Concept UI M0473942
Preferred term Tanderil



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