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Descriptor English: Erlotinib Hydrochloride
Descriptor Spanish: Clorhidrato de Erlotinib
Descriptor clorhidrato de erlotinib
Scope note: Derivado de la quinazolina y ANTINEOPLÁSICO que funciona como un INHIBIDOR DE LA PROTEÍNA QUINASA para la tirosina quinasa asociada a EGFR. Se utiliza en el tratamiento del CÁNCER DE PULMÓN DE CÉLULAS NO PEQUEÑAS.
Descriptor Portuguese: Cloridrato de Erlotinib
Descriptor French: Chlorhydrate d'erlotinib
Entry term(s): 11C erlotinib
11C-erlotinib
358,774, CP
358774, CP
CP 358,774
CP 358774
CP-358,774
CP-358774
CP358,774
CP358774
Erlotinib
Erlotinib HCl
HCl, Erlotinib
Hydrochloride, Erlotinib
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
OSI 774
OSI-774
OSI774
Tarceva
Tree number(s): D03.633.100.786.375
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069347
Scope note: A quinazoline derivative and ANTINEOPLASTIC AGENT that functions as a PROTEIN KINASE INHIBITOR for EGFR associated tyrosine kinase. It is used in the treatment of NON-SMALL CELL LUNG CANCER.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number: DA87705X9K
Public MeSH Note: 2016; ERLOTINIB HYDROCHLORIDE was indexed under QUINAZOLINES 1999-2015
History Note: 2016 (1999)
DeCS ID: 55936
Unique ID: D000069347
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/10
Revision Date: 2016/05/31
Erlotinib Hydrochloride - Preferred
Concept UI M0493669
Scope note A quinazoline derivative and ANTINEOPLASTIC AGENT that functions as a PROTEIN KINASE INHIBITOR for EGFR associated tyrosine kinase. It is used in the treatment of NON-SMALL CELL LUNG CANCER.
Preferred term Erlotinib Hydrochloride
Entry term(s) Erlotinib HCl
HCl, Erlotinib
Hydrochloride, Erlotinib
OSI-774 - Narrower
Concept UI M0433509
Preferred term OSI-774
Entry term(s) OSI 774
OSI774
CP 358774 - Narrower
Concept UI M0454216
Preferred term CP 358774
Entry term(s) 358,774, CP
358774, CP
CP 358,774
CP-358,774
CP-358774
CP358,774
CP358774
11C-erlotinib - Narrower
Concept UI M000597783
Preferred term 11C-erlotinib
Entry term(s) 11C erlotinib
Erlotinib - Broader
Concept UI M0350388
Preferred term Erlotinib
Entry term(s) N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Tarceva - Narrower
Concept UI M0434471
Preferred term Tarceva



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