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Descriptor English: Thiabendazole
Descriptor Spanish: Tiabendazol
Descriptor tiabendazol
Scope note: Benzoimidazol sustituído en la posición 2, inicialmente introducido en 1962. Es activo frente a diversos nemátodos y constituye el fármaco de elección para el tratamiento de la ESTRONGILOIDIASIS. Tiene efectos colaterales sobre el SISTEMA NERVIOSO CENTRAL y también es potencialmente hepatotóxico. (de Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Descriptor Portuguese: Tiabendazol
Descriptor French: Tiabendazol
Entry term(s): 2-(4'-Thiazolyl)Benzimidazole
Mintesol
Mintezol
Omnizole
Thibendole
Tiabendazol
Tree number(s): D02.886.675.840
D03.383.129.708.824
D03.633.100.103.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013827
Scope note: 2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anthelmintics
Registry Number: N1Q45E87DT
CAS Type 1 Name: 1H-Benzimidazole, 2-(4-thiazolyl)-
Public MeSH Note: 65
History Note: 65(63)
DeCS ID: 14204
Unique ID: D013827
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/01
Thiabendazole - Preferred
Concept UI M0021313
Scope note 2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Preferred term Thiabendazole
Entry term(s) 2-(4'-Thiazolyl)Benzimidazole
Thibendole
Tiabendazol
Mintezol - Narrower
Concept UI M0021314
Preferred term Mintezol
Omnizole - Narrower
Concept UI M0353570
Preferred term Omnizole
Mintesol - Narrower
Concept UI M0353571
Preferred term Mintesol



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