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Descriptor English: Factor VIII
Descriptor Spanish: Factor VIII
Descriptor factor VIII
Entry term(s) actividad procoagulante del factor VIII
antígeno coagulante del factor VIII
factor 8
factor 8C
factor VIII de la coagulación
factor VIIIC
factor ocho
tromboplastinógeno
Scope note: Factor VIII de la coagulación sanguínea. Factor antihemofílico que forma parte del complejo factor VIII-factor de von Willebrand. El factor VIII se produce en el hígado y actúa en la vía intrínseca de la coagulación de la sangre. Actúa como cofactor en la activación del factor X y pequeñas cantidades de trombina incrementan notablemente esta acción.
Descriptor Portuguese: Fator VIII
Descriptor French: Facteur VIII
Entry term(s): Blood Coagulation Factor VIII
Coagulation Factor VIII
F VIII C
F VIII-C
Factor 8
Factor 8 C
Factor Eight
Factor VIII Clotting Antigen
Factor VIII Coagulant Antigen
Factor VIII Procoagulant Activity
Factor VIIIC
Hyate C
Hyate-C
HyateC
Hyatt C
Hyatt-C
HyattC
Thromboplastinogen
Tree number(s): D12.776.124.125.350
D12.776.811.286
D23.119.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005169
Scope note: Factor VIII of blood coagulation. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Hemophilia A
Pharm Action: Coagulants
Registry Number: 9001-27-8
CAS Type 1 Name: Blood-coagulation factor VIII, complex
DeCS ID: 22172
Unique ID: D005169
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/02/24
Factor VIII - Preferred
Concept UI M0008146
Scope note Factor VIII of blood coagulation. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Preferred term Factor VIII
Entry term(s) Blood Coagulation Factor VIII
Coagulation Factor VIII
Factor 8
Factor Eight
Thromboplastinogen
Hyatt-C - Narrower
Concept UI M0008148
Preferred term Hyatt-C
Entry term(s) Hyate C
Hyate-C
HyateC
Hyatt C
HyattC
Factor VIIIC - Related but not broader or narrower
Concept UI M0008151
Preferred term Factor VIIIC
Entry term(s) F VIII C
F VIII-C
Factor 8 C
Factor VIII Coagulant Antigen - Related but not broader or narrower
Concept UI M0008149
Preferred term Factor VIII Coagulant Antigen
Entry term(s) Factor VIII Clotting Antigen
Factor VIII Procoagulant Activity - Related but not broader or narrower
Concept UI M0008153
Preferred term Factor VIII Procoagulant Activity



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