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Descriptor English: Topiramate
Descriptor Spanish: Topiramato
Descriptor topiramato
Entry term(s) Epitomax
McN 4853
McN-4853
McN4853
Topamax
USL255
sulfamato de 2,3-4,5-bis-O-(1-metiletiliden)-beta-D-fructopiranosa
Scope note: Análogo de la fructosa con sustitución de sulfamato que se identificó originalmente como hipoglucemiante. Se usa para el tratamiento de la EPILEPSIA y de los TRASTORNOS MIGRAÑOSOS, y también puede favorecer la pérdida de peso.
Descriptor Portuguese: Topiramato
Descriptor French: Topiramate
Entry term(s): 2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
Epitomax
McN 4853
McN-4853
McN4853
Topamax
USL255
Tree number(s): D09.947.875.359.250.500
D09.947.875.465.354.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077236
Scope note: A sulfamate-substituted fructose analog that was originally identified as a hypoglycemic agent. It is used for the treatment of EPILEPSY and MIGRAINE DISORDERS, and may also promote weight loss.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticonvulsants
Hypoglycemic Agents
Registry Number: 0H73WJJ391
Public MeSH Note: 2019; TOPIRAMATE was indexed under FRUCTOSE 1987-2018
History Note: 2019 (1987)
DeCS ID: 57558
Unique ID: D000077236
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19
Topiramate - Preferred
Concept UI M0148600
Scope note A sulfamate-substituted fructose analog that was originally identified as a hypoglycemic agent. It is used for the treatment of EPILEPSY and MIGRAINE DISORDERS, and may also promote weight loss.
Preferred term Topiramate
Entry term(s) 2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
Epitomax - Narrower
Concept UI M000639964
Preferred term Epitomax
McN 4853 - Narrower
Concept UI M0148598
Preferred term McN 4853
Entry term(s) McN-4853
McN4853
USL255 - Narrower
Concept UI M0588327
Preferred term USL255
Topamax - Narrower
Concept UI M0398827
Preferred term Topamax



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