Search on: V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1 
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Descriptor English:   V-Set Domain-Containing T-Cell Activation Inhibitor 1 
Descriptor Spanish:   Inhibidor 1 de la Activación de Células T con Dominio V-Set 
Descriptor Portuguese:   Inibidor 1 da Ativação de Células T com Domínio V-Set 
Synonyms English:   B7H4 Immune Costimulatory Protein
Immune Costimulatory Protein B7 H4
Immune Costimulatory Protein B7-H4
T Cell Costimulatory Molecule B7x
T-Cell Costimulatory Molecule B7x
V Set Domain Containing T Cell Activation Inhibitor 1  
Tree Number:   D12.776.467.150.900
D12.776.543.095.900
D23.050.301.285.900
D23.529.168.900
Definition English:   A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION. 
See Related English:   Immunoglobulin Domains
 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54626 
Unique Identifier:   D060907 

Occurrence in VHL:
 
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