Search on: VACCINES, DNA 
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Descriptor English:   Vaccines, DNA 
Descriptor Spanish:   Vacunas de ADN 
Descriptor Portuguese:   Vacinas de DNA 
Synonyms English:   DNA Vaccines
DNA Vaccines, Naked
DNA Vaccines, Recombinant
Naked DNA Vaccines
Nucleic Acid Vaccines
Polynucleotide Vaccines
Recombinant DNA Vaccines
Vaccines, Naked DNA
Vaccines, Nucleic Acid
Vaccines, Polynucleotide
Vaccines, Recombinant DNA  
Tree Number:   D12.776.828.868.910
Definition English:   Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers. 
Indexing Annotation English:   vaccines composed of recombinant DNA vectors encoding antigens
History Note English:   97 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism MI microbiology
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine VI virology
Record Number:   33063 
Unique Identifier:   D019444 

Occurrence in VHL: