Search on: VENTURICIDINS 
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Descriptor English:   Venturicidins 
Descriptor Spanish:   Venturicidinas 
Descriptor Portuguese:   Venturicidinas 
Tree Number:   D02.540.800
Definition English:   Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function. 
Indexing Annotation English:   uncoupling agents & antifungal antibiotics; from Streptomyces
Pharmacological Action:   Antifungal Agents
Uncoupling Agents
 
History Note English:   91(77); was see under LACTONES 1977-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   15103 
Unique Identifier:   D014698 

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