Search on: VIRAL INSERTIONAL MUTAGENESIS 
Descriptors Found: 1
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Descriptor English:   Mutagenesis, Insertional 
Descriptor Spanish:   Mutagénesis Insercional 
Descriptor Portuguese:   Mutagênese Insercional 
Synonyms English:   Activation, Insertional
Activations, Insertional
Cassette Mutagenesis
Gene Insertions
Insertion Mutations
Insertion, Gene
Insertion, Sequence
Insertional Activations
Insertional Mutagenesis, Viral
Insertions, Gene
Insertions, Sequence
Linker Insertion Mutagenesis
Mutagenesis, Linker-Insertion
Mutagenesis, Viral Insertional
Mutation, Insertion
Mutations, Insertion
Sequence Insertions
Gene Insertion
Insertion Mutation
Insertional Activation
Insertional Mutagenesis
Linker-Insertion Mutagenesis
Mutagenesis, Cassette
Sequence Insertion
Viral Insertional Mutagenesis  
Tree Number:   E05.393.420.601.550
G05.365.590.575
G05.558.550
Definition English:   Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation. 
See Related English:   DNA Transposable Elements
 
History Note English:   91 
Allowable Qualifiers English:  
DE drug effects EC economics
GE genetics HI history
IM immunology IS instrumentation
MT methods PH physiology
RE radiation effects ST standards
SN statistics & numerical data UT utilization
Record Number:   29057 
Unique Identifier:   D016254 

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