Search on: VISCERAL EPITHELIAL CELLS, GLOMERULAR 
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Descriptor English:   Podocytes 
Descriptor Spanish:   Podocitos 
Descriptor Portuguese:   Podócitos 
Synonyms English:   Epithelial Cells, Glomerular Visceral
Glomerular Visceral Epithelial Cells
Podocyte
Visceral Epithelial Cells, Glomerular  
Tree Number:   A05.810.453.324.359.372.650
A05.810.453.736.520.720
A11.436.720
Definition English:   Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels. They enwrap the KIDNEY GLOMERULUS capillaries with their cell surface extensions forming a filtration structure. The pedicels of neighboring podocytes interdigitate with each other leaving between them filtration slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit diaphragm, and provide the last barrier to protein loss in the KIDNEY. 
History Note English:   2006 
Allowable Qualifiers English:  
CH chemistry CL classification
CY cytology DE drug effects
EN enzymology IM immunology
ME metabolism MI microbiology
PS parasitology PA pathology
PH physiology RE radiation effects
TR transplantation UL ultrastructure
VI virology  
Record Number:   50371 
Unique Identifier:   D050199 

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