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Descriptor English:   Nicotinamide Phosphoribosyltransferase 
Descriptor Spanish:   Nicotinamida Fosforribosiltransferasa 
Descriptor Portuguese:   Nicotinamida Fosforribosiltransferase 
Synonyms English:   Colony-Enhancing Factor, Pre-B-Cell
NAMPT Protein
NMN Pyrophosphorylase
Phosphoribosyltransferase, Nicotinamide
Pre B Cell Colony Enhancing Factor
Pre-B-Cell Colony-Enhancing Factor
Tree Number:   D08.811.913.400.725.575
Definition English:   An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). 
History Note English:   2008 (1982) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52725 
Unique Identifier:   D054409 

Occurrence in VHL: