Search on: VITAMIN B 6 
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Descriptor English:   Vitamin B 6 
Descriptor Spanish:   Vitamina B 6 
Descriptor Portuguese:   Vitamina B 6 
Synonyms English:   Vitamin B6  
Tree Number:   D03.383.725.676.925
Definition English:   VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine. 
Indexing Annotation English:   /ther use: coordinate with disease /drug ther, not /diet ther
Pharmacological Action:   Vitamin B Complex
 
Entry Combination - descr/qualif English:   Vitamin B 6/deficiency use Vitamin B 6 Deficiency
 
History Note English:   2002; use PYRIDOXINE 1963-2001 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   36121 
Unique Identifier:   D025101 

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