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Descriptor English:   Patch-Clamp Techniques 
Descriptor Spanish:   Técnicas de Placa-Clamp 
Descriptor Portuguese:   Técnicas de Patch-Clamp 
Synonyms English:   Patch Clamp Technics
Patch Clamp Techniques
Patch-Clamp Technic
Patch-Clamp Technics
Patch-Clamp Technique
Recording, Whole-Cell
Recordings, Whole-Cell
Technic, Patch-Clamp
Technic, Voltage-Clamp
Technics, Patch-Clamp
Technics, Voltage-Clamp
Technique, Patch-Clamp
Technique, Voltage-Clamp
Techniques, Patch-Clamp
Techniques, Voltage-Clamp
Voltage Clamp Technics
Voltage Clamp Techniques
Voltage-Clamp Technic
Voltage-Clamp Technics
Voltage-Clamp Technique
Voltage-Clamp Techniques
Whole Cell Recording
Whole-Cell Recording
Whole-Cell Recordings  
Tree Number:   E05.200.500.905
Definition English:   An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used. 
Indexing Annotation English:   a cytol technique for removing a tiny patch of plasma membrane; NIM
History Note English:   95 
Allowable Qualifiers English:  
CL classification EC economics
ES ethics HI history
IS instrumentation MT methods
ST standards SN statistics & numerical data
TD trends VE veterinary
Record Number:   32097 
Unique Identifier:   D018408 

Occurrence in VHL: