Search on: VOLTAGE-GATED SODIUM CHANNEL TYPE 8 SUBUNIT ALPHA 
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Descriptor English:   NAV1.6 Voltage-Gated Sodium Channel 
Descriptor Spanish:   Canal de Sodio Activado por Voltaje NAV1.6 
Descriptor Portuguese:   Canal de Sódio Disparado por Voltagem NAV1.6 
Synonyms English:   NAV1.6 Voltage Gated Sodium Channel
SCN8A Sodium Channel alpha Subunit
Type 8 Voltage Gated Sodium Channel
Type 8 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 8
Voltage Gated Sodium Channel Type 8 Subunit alpha
Voltage-Gated Sodium Channel Type 8
Voltage-Gated Sodium Channel Type 8 Subunit alpha  
Tree Number:   D12.776.157.530.400.875.750.600
D12.776.543.550.450.875.750.600
D12.776.543.585.400.875.750.600
D12.776.631.960.600
Definition English:   A voltage-gated sodium channel subtype found widely expressed in neurons of the central and peripheral nervous systems. Defects in the SCN8A gene which codes for the alpha subunit of this sodium channel are associated with ATAXIA and cognitive deficits. 
Entry Combination - descr/qualif English:   NAV1.6 Voltage-Gated Sodium Channel/antagonists & inhibitors use Voltage-Gated Sodium Channel Blockers
NAV1.6 Voltage-Gated Sodium Channel/agonists use Voltage-Gated Sodium Channel Agonists
 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54952 
Unique Identifier:   D062557 

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