Search on: VOLTAGE-GATED SODIUM CHANNELS 
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Descriptor English:   Voltage-Gated Sodium Channels 
Descriptor Spanish:   Canales de Sodio Activados por Voltaje 
Descriptor Portuguese:   Canais de Sódio Disparados por Voltagem 
Synonyms English:   Channels, Voltage-Gated Sodium
Sodium Channels, Voltage Gated
Sodium Channels, Voltage-Gated
Voltage Gated Sodium Channels  
Tree Number:   D12.776.157.530.400.875.750
D12.776.543.550.450.875.750
D12.776.543.585.400.875.750
D12.776.631.960
Definition English:   A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity. 
Indexing Annotation English:   general or unspecified; prefer specifics
Entry Combination - descr/qualif English:   Voltage-Gated Sodium Channels/antagonists & inhibitors use Voltage-Gated Sodium Channel Blockers
Voltage-Gated Sodium Channels/agonists use Voltage-Gated Sodium Channel Agonists
 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54946 
Unique Identifier:   D061566 

Occurrence in VHL:
 
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