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Descriptor English: Butyrophilins
Descriptor Spanish: Butirofilinas
Descriptor butirofilinas
Entry term(s) butirofilina
Scope note: Familia de glucoproteínas de la membrana de los mamíferos caracterizada por DOMINIOS DE INMUNOGLOBULINA extracelulares. Algunos miembros también tienen un DOMINIO B30.2-SPRY o DOMINIO SPRY intracelular. La proteína butirofilina (BTN) se expresa en el EPITELIO DE LA GLÁNDULA MAMARIA durante la LACTANCIA, mientras que otros miembros se expresan ampliamente en otros tejidos como el músculo esquelético, el intestino, las CÉLULAS ERITROIDES (proteína ERMAP) y el tejido nervioso (GLUCOPROTEÍNA OLIGODENDROCITARIA DE LA MIELINA).
Descriptor Portuguese: Butirofilinas
Descriptor French: Butyrophilines
Entry term(s): Butyrophilin
Tree number(s): D12.776.395.550.114
D12.776.543.550.195
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071797
Scope note: A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; BUTRYOPHILINS was indexed under MEMBRANE GLYCOPROTEINS 1988-2016 and under GLYCOPROTEINS 1981-1987
History Note: 2017 (1981)
DeCS ID: 56620
Unique ID: D000071797
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/20
Butyrophilins - Preferred
Concept UI M000615546
Scope note A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN).
Preferred term Butyrophilins
Entry term(s) Butyrophilin



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