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Descriptor English: Canagliflozin
Descriptor Spanish: Canagliflozina
Descriptor canagliflozina
Scope note: Inhibidor del TRANSPORTADOR 2 DE SODIO-GLUCOSA derivado de glucósido, que estimula la excreción urinaria de glucosa mediante la supresión de la reabsorción renal de glucosa. Se utiliza para controlar los niveles de GLUCEMIA en pacientes con DIABETES TIPO 2.
Descriptor Portuguese: Canagliflozina
Descriptor French: Canagliflozine
Entry term(s): 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene - T777973
Canagliflozin Hemihydrate
Canagliflozin, Anhydrous
Invokana
Tree number(s): D02.886.778.075
D03.383.903.075
D09.408.348.113
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068896
Scope note: A glucoside-derived SODIUM-GLUCOSE TRANSPORTER 2 inhibitor that stimulates urinary excretion of glucose by suppressing renal glucose reabsorption. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Sodium-Glucose Transporter 2 Inhibitors
Registry Number: 0SAC974Z85
Public MeSH Note: 2016; CANAGLIFLOZIN was indexed under GLUCOSIDES and THIOPHENES 2014-2015
History Note: 2016 (2014)
DeCS ID: 55908
Unique ID: D000068896
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2018/02/28
Canagliflozin - Preferred
Concept UI M0550188
Scope note A glucoside-derived SODIUM-GLUCOSE TRANSPORTER 2 inhibitor that stimulates urinary excretion of glucose by suppressing renal glucose reabsorption. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
Preferred term Canagliflozin
Invokana - Narrower
Concept UI M000604077
Preferred term Invokana
Canagliflozin Hemihydrate - Narrower
Concept UI M000638386
Preferred term Canagliflozin Hemihydrate
Canagliflozin, Anhydrous - Related but not broader or narrower
Concept UI M000613688
Preferred term Canagliflozin, Anhydrous
Entry term(s) 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene - T777973



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