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Descriptor English: Saposins
Descriptor Spanish: Saposinas
Descriptor saposinas
Entry term(s) saposina
Scope note: Grupo de cuatro proteínas homólogas activadoras de esfingolípidos formadas a partir de la escisión proteolítica de una molécula común precursora de una proteína denominada prosaposina.
Descriptor Portuguese: Saposinas
Descriptor French: Saposines
Entry term(s): Co beta Glucosidase
Co-beta-Glucosidase
Coglucosidase
Gaucher Activator Protein
Glucosylceramidase Activator
SAP 1 Sphingolipid Activator
SAP A Protein
SAP C Protein
SAP D Protein
SAP-1 Sphingolipid Activator
SAP-A Protein
SAP-C Protein
SAP-D Protein
Saposin
Saposin A
Saposin B
Saposin C
Saposin D
Sphingolipid Activator Protein 1
Sphingolipid Activator Protein 2
Sphingolipid Activator Protein-1
Sphingolipid Activator, SAP-1
Testibumin
beta Glucosidase Activator Protein
beta Glucosidase Stimulating Protein
beta-Glucosidase Activator Protein
beta-Glucosidase Stimulating Protein
Tree number(s): D08.211.790.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D049231
Scope note: A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Glycoproteins (1977-2004)
Public MeSH Note: 2005; SAPOSIN A was indexed under GLYCOPROTEINS 1989-2004; SAPOSIN B was indexed under GLYCOPROTEINS 1993-2004 & PROTEINS 1981-1992; SAPOSIN D was indexed under GLYCOPROTEINS 1988-2004
History Note: 2005(1977)
DeCS ID: 38691
Unique ID: D049231
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2020/05/27
Saposins - Preferred
Concept UI M0463564
Scope note A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin.
Preferred term Saposins
Entry term(s) Saposin
Testibumin
Saposin B - Narrower
Concept UI M0063222
Preferred term Saposin B
Entry term(s) SAP 1 Sphingolipid Activator
SAP-1 Sphingolipid Activator
Sphingolipid Activator Protein 1
Sphingolipid Activator Protein-1
Sphingolipid Activator, SAP-1
Saposin D - Narrower
Concept UI M0160576
Preferred term Saposin D
Entry term(s) SAP D Protein
SAP-D Protein
Saposin A - Narrower
Concept UI M0165439
Preferred term Saposin A
Entry term(s) SAP A Protein
SAP-A Protein
Saposin C - Narrower
Concept UI M0097524
Preferred term Saposin C
Entry term(s) Co beta Glucosidase
Co-beta-Glucosidase
Coglucosidase
Gaucher Activator Protein
Glucosylceramidase Activator
SAP C Protein
SAP-C Protein
Sphingolipid Activator Protein 2
beta Glucosidase Activator Protein
beta Glucosidase Stimulating Protein
beta-Glucosidase Activator Protein
beta-Glucosidase Stimulating Protein



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