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Descritor Inglês:   Copper-transporting ATPases 
Descritor Espanhol:   ATPasas Transportadoras de Cobre 
Descritor Português:   ATPases Transportadoras de Cobre 
Sinônimos Inglês:   ATP7A Protein
ATP7B Cu-binding P type ATPase
ATPase Copper Transporting alpha
ATPase, Cu++ transporting, beta Polypeptide (Wilson Disease)
Copper Pump 1
Copper-transporting ATPase
Copper-transporting ATPase 1
Copper-transporting ATPase 2
Copper-transporting Adenosine Triphosphatases
Cu(+)-transporting ATPases
Cu-transporting ATPases
Menkes Disease-associated Protein
PINA Enzyme
Pineal Night-specific ATPase
Wilson Disease Cu-binding P Type ATPase
Wilson Disease Protein
ATP7B Cu binding P type ATPase
ATPase 1, Copper-transporting
ATPase, Copper-transporting
ATPase, Pineal Night-specific
ATPases, Copper-transporting
ATPases, Cu-transporting
Adenosine Triphosphatases, Copper-transporting
Copper transporting ATPase
Copper transporting ATPase 1
Copper transporting ATPase 2
Copper transporting ATPases
Copper transporting Adenosine Triphosphatases
Cu transporting ATPases
Menkes Disease associated Protein
Night-specific ATPase, Pineal
Pineal Night specific ATPase
Triphosphatases, Copper-transporting Adenosine
Wilson Disease Cu binding P Type ATPase  
Categoria:   D08.811.277.040.025.314.500
D12.776.157.530.450.250.656
D12.776.157.530.813.500
D12.776.543.585.450.250.656
D12.776.543.585.813.500
Definição Inglês:   P-type ATPases which transport copper ions across membranes in prokaryotic and eukaryotic cells. They possess a conserved CYSTEINE-HISTIDINE-SERINE (CPx) amino acid motif within their transmembrane helices that functions in cation translocation and catalytic activation, and an N-terminal copper-binding CxxC motif that regulates enzyme activity. They play essential roles in intracellular copper homeostasis through regulating the uptake, efflux and storage of copper ions, and in cuproprotein biosynthesis. 
Relacionados Inglês:   Hepatolenticular Degeneration
Menkes Kinky Hair Syndrome
 
Nota Histórica Inglês:   2018 (1994) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   56998 
Identificador Único:   D000073840 

Ocorrência na BVS:
 
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