Pesquisa sobre: MFN=57015 
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Descritor Inglês:   Aldo-Keto Reductases 
Descritor Espanhol:   Aldo-Ceto Reductasas 
Descritor Português:   Aldo-Ceto Redutases 
Sinônimos Inglês:   Aldo-Keto Reductase
Aldo-Keto Reductase Family
Aldo-Keto Reductase Superfamily
Aldo Keto Reductase
Aldo Keto Reductase Family
Aldo Keto Reductase Superfamily
Aldo Keto Reductases
Reductase, Aldo-Keto
Reductases, Aldo-Keto  
Categoria:   D08.811.682.047.150.700.156
D08.811.682.047.820.284
Definição Inglês:   A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57015 
Identificador Único:   D000074408 

Ocorrência na BVS:
 
MEDLINE    

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