Pesquisa sobre: MFN=57024 
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Descritor Inglês:   NADPH Oxidase 2 
Descritor Espanhol:   NADPH Oxidasa 2 
Descritor Português:   NADPH Oxidase 2 
Sinônimos Inglês:   CYBB Protein
Chronic Granulomatous Disease Protein
Cytochrome B-245 Beta Chain
GP91-PHOX Protein
NOX2 Protein
Cytochrome B 245 Beta Chain
GP91 PHOX Protein
Oxidase 2, NADPH  
Categoria:   D08.811.682.608.575.875
Definição Inglês:   An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57024 
Identificador Único:   D000074662 

Ocorrência na BVS: