Pesquisa sobre: MFN=57030 
Descritores Encontrados: 1
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Descritor Inglês:   Positive Regulatory Domain I-Binding Factor 1 
Descritor Espanhol:   Factor 1 de Unión al Dominio 1 de Regulación Positiva 
Descritor Português:   Fator 1 de Ligação ao Domínio I Regulador Positivo 
Sinônimos Inglês:   B Lymphocyte-Induced Maturation Protein 1
BLIMP1 Protein
PRDI-BF1 Protein
PRDM1 Protein
B Lymphocyte Induced Maturation Protein 1
PRDI BF1 Protein
Positive Regulatory Domain I Binding Factor 1  
Categoria:   D08.811.913.555.500.800.700
D12.776.260.703.650
D12.776.930.780.904
Definição Inglês:   A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs. 
Relacionados Inglês:   PR-SET Domains
 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57030 
Identificador Único:   D000074462 

Ocorrência na BVS:
 
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