Pesquisa sobre: MFN=57036 
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Descritor Inglês:   Disks Large Homolog 4 Protein 
Descritor Espanhol:   Homólogo 4 de la Proteína Discs Large 
Descritor Português:   Proteína 4 Homóloga a Disks-Large 
Sinônimos Inglês:   Discs Large Homolog 4 Protein
PSD-95 Protein
PSD95 Protein
Postsynaptic Density Protein 95
SAP-90 Protein
SAP90 Protein
Synapse-Associated Protein 90
PSD 95 Protein
SAP 90 Protein
Synapse Associated Protein 90  
Categoria:   D08.811.913.696.650.450.750
Definição Inglês:   A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. 
Relacionados Inglês:   SAP90-PSD95 Associated Proteins
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57036 
Identificador Único:   D000076122 

Ocorrência na BVS: