Pesquisa sobre: MFN=57048 
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Descritor Inglês:   Angiopoietin-like 4 Protein 
Descritor Espanhol:   Proteína 4 Similar a la Angiopoyetina 
Descritor Português:   Proteína 4 Semelhante a Angiopoietina 
Sinônimos Inglês:   ANGPTL4 Protein
Angiopoietin-like Protein 4
Angiopoietin-related Protein 4
Angiopoietin like 4 Protein
Angiopoietin like Protein 4
Angiopoietin related Protein 4  
Categoria:   D12.644.276.100.050.500
D12.776.467.100.050.500
D23.529.100.050.500
Definição Inglês:   A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57048 
Identificador Único:   D000075803 

Ocorrência na BVS:
 
MEDLINE    

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