Pesquisa sobre: MFN=57063 
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Descritor Inglês:   Serine Peptidase Inhibitor Kazal-Type 5 
Descritor Espanhol:   Inhibidor de Serinpeptidasas Tipo Kazal-5 
Descritor Português:   Inibidor de Serinopeptidase do Tipo Kazal 5 
Sinônimos Inglês:   LEKTI Protein
Lympho-Epithelial Kazal-Type Inhibitor
SPINK5 Protein
Serine Protease Inhibitor Kazal-Type 5
Inhibitor, Lympho-Epithelial Kazal-Type
Kazal-Type Inhibitor, Lympho-Epithelial
Lympho Epithelial Kazal Type Inhibitor
Serine Peptidase Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal Type 5  
Categoria:   D12.644.822.750.250
Definição Inglês:   A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME. 
Relacionados Inglês:   Kazal Motifs
Netherton Syndrome
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57063 
Identificador Único:   D000074163 

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