Pesquisa sobre: MFN=57077 
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Descritor Inglês:   TRPC6 Cation Channel 
Descritor Espanhol:   Canal Catiónico TRPC6 
Descritor Português:   Canal de Cátion TRPC6 
Sinônimos Inglês:   TRPC6
Transient Receptor Potential Cation Channel Subfamily C, Member 6
Cation Channel, TRPC6
Channel, TRPC6 Cation  
Categoria:   D12.776.157.530.400.150.850
Definição Inglês:   A non-selective, calcium permeant TRPC cation channel that contains four ANKYRIN REPEATS and is activated by DIACYLGLYCEROL independently of PROTEIN KINASE C. It is expressed in placenta, lung, spleen, ovary and the small intestine, as well as by PODOCYTES in the kidney glomerulus. Mutations in the TRPC6 gene are associated with FOCAL SEGMENTAL GLOMERULOSCLEROSIS type 2. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57077 
Identificador Único:   D000074287 

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