Pesquisa sobre: MFN=57079 
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Descritor Inglês:   Anoctamins 
Descritor Espanhol:   Anoctaminas 
Descritor Português:   Anoctaminas 
Sinônimos Inglês:   Anoctamin
TMEM16 Protein Family
TMEM16 Proteins
Protein Family, TMEM16  
Categoria:   D12.776.157.530.400.175.032
Definição Inglês:   A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57079 
Identificador Único:   D000075368 

Ocorrência na BVS: