Pesquisa sobre: MFN=57087 
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Descritor Inglês:   Solute Carrier Family 22 Member 5 
Descritor Espanhol:   Miembro 5 de la Familia 22 de Transportadores de Solutos 
Descritor Português:   Membro 5 da Família 22 de Carreadores de Soluto 
Sinônimos Inglês:   High-Affinity Carnitine Transporter
OCTN2 Protein
Organic Cation-Carnitine Transporter 2
SLC22A5 Protein
Sodium-Dependent Carnitine Cotransporter
Carnitine Cotransporter, Sodium-Dependent
Carnitine Transporter, High-Affinity
High Affinity Carnitine Transporter
Organic Cation Carnitine Transporter 2
Sodium Dependent Carnitine Cotransporter
Transporter, High-Affinity Carnitine  
Categoria:   D12.776.157.530.450.250.812.750
Definição Inglês:   A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57087 
Identificador Único:   D000074058 

Ocorrência na BVS: