Pesquisa sobre: MFN=57108 
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Descritor Inglês:   Elongin 
Descritor Espanhol:   Elonguina 
Descritor Português:   Elonguina 
Sinônimos Inglês:   EloA Protein
EloB Protein
EloC Protein
Elongin A
Elongin B
Elongin C
Elongin Complex
SIII Elongation Factor
Transcription Factor SIII
Complex, Elongin
Elongation Factor, SIII
SIII, Transcription Factor  
Categoria:   D12.776.260.197
Definição Inglês:   A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity. 
Nota Histórica Inglês:   2018 (1995) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57108 
Identificador Único:   D000075065 

Ocorrência na BVS: