Pesquisa sobre: MFN=57113 
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Descritor Inglês:   Zinc Finger E-box Binding Homeobox 2 
Descritor Espanhol:   Caja Homeótica 2 de Unión a E-Box con Dedos de Zinc 
Descritor Português:   Homeobox 2 de Ligação a E-box com Dedos de Zinco 
Sinônimos Inglês:   Smad-Interacting Protein 1
Zeb2 Transcription Factor
Zinc Finger E-box Binding Homeobox 2 Protein
Smad Interacting Protein 1
Transcription Factor, Zeb2
Zinc Finger E box Binding Homeobox 2
Zinc Finger E box Binding Homeobox 2 Protein  
Categoria:   D12.776.260.400.883
D12.776.260.703.700
D12.776.930.780.918
Definição Inglês:   A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57113 
Identificador Único:   D000074165 

Ocorrência na BVS:
 
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