Pesquisa sobre: MFN=57115 
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Descritor Inglês:   Promyelocytic Leukemia Zinc Finger Protein 
Descritor Espanhol:   Proteína de la Leucemia Promielocítica con Dedos de Zinc 
Descritor Português:   Proteína com Dedos de Zinco da Leucemia Promielocítica 
Sinônimos Inglês:   PLZF Protein
Promyelocytic Leukaemia Zinc Finger Protein
ZBTB16 Protein
Zinc Finger and BTB Domain Containing 16 Protein  
Categoria:   D12.776.260.522.625
D12.776.930.375.625
Definição Inglês:   A Krupple-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57115 
Identificador Único:   D000075722 

Ocorrência na BVS:
 
MEDLINE    

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