Pesquisa sobre: MFN=57123 
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Descritor Inglês:   Cell Adhesion Molecule-1 
Descritor Espanhol:   Molécula 1 de Adhesión Celular 
Descritor Português:   Molécula 1 de Adesão Celular 
Sinônimos Inglês:   CADM1 Protein
IGSF4 Protein
TSLC1 Protein
Tumor Suppressor in Lung Cancer 1 Protein
Adhesion Molecule-1, Cell
Cell Adhesion Molecule 1
Molecule-1, Cell Adhesion  
Categoria:   D12.776.395.550.200.115
Definição Inglês:   A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation. 
Relacionados Inglês:   Immunoglobulin Domains
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57123 
Identificador Único:   D000075982 

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