Pesquisa sobre: MFN=57130 
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Descritor Inglês:   Pancreatitis-Associated Proteins 
Descritor Espanhol:   Proteínas Asociadas a Pancreatitis 
Descritor Português:   Proteínas Associadas a Pancreatite 
Sinônimos Inglês:   Pancreatitis-Associated Protein
Pancreatitis-Associated Protein-1
Regenerating Islet-Derived Protein 3
Regenerating Islet-Derived Proteins
Pancreatitis Associated Protein
Pancreatitis Associated Protein 1
Pancreatitis Associated Proteins
Regenerating Islet Derived Protein 3
Regenerating Islet Derived Proteins  
Categoria:   D12.776.503.280.578
Definição Inglês:   C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker. 
Nota Histórica Inglês:   2018 (1992) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57130 
Identificador Único:   D000073718 

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