Pesquisa sobre: MFN=57143 
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Descritor Inglês:   NEDD8 Protein 
Descritor Espanhol:   Proteína NEDD8 
Descritor Português:   Proteína NEDD8 
Sinônimos Inglês:   NEDD-8 Protein
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Ubiquitin-like Protein NEDD8
NEDD 8 Protein
NEDD8, Ubiquitin-like Protein
Neural Precursor Cell Expressed Developmentally Down Regulated Protein 8
Ubiquitin like Protein NEDD8  
Categoria:   D12.776.947.218
Definição Inglês:   A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57143 
Identificador Único:   D000075687 

Ocorrência na BVS:
 
MEDLINE    

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