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Descriptor English: Folic Acid Deficiency
Descriptor Spanish: Deficiencia de Ácido Fólico
Descriptor deficiencia de ácido fólico
Entry term(s) déficit de ácido fólico
Scope note: Enfermedad nutricional producida por déficit de ÁCIDO FÓLICO en la dieta. Muchos tejidos vegetales y animales contienen ácido fólico y es abundante en las hortalizas de hojas verdes, levadura, hígado y setas, pero se destruye por la cocción prolongada. El alcohol interfiere con su absorción y metabolismo intermediario. Puede aparece déficit de ácido fólico en casos de tratamientos anticonvulsivantes prolongados o por el uso de anticonceptivos orales. Esta deficiencia causa anemia, anemia macrocítica y anemia megaloblástica. No es distinguible del déficit de vitamina B12 en las muestras de médula ósea y de sangre periférica, pero no presenta las lesiones neurológicas que acompañan a la deficiencia de vitamina B12. (Traducción libre del original: Merck Manual, 16th ed)
Descriptor Portuguese: Deficiência de Ácido Fólico
Descriptor French: Carence en acide folique
Entry term(s): Acid Deficiencies, Folic
Acid Deficiency, Folic
Deficiencies, Folic Acid
Deficiency, Folic Acid
Folic Acid Deficiencies
Tree number(s): C18.654.521.500.133.699.308
SP6.990.625.344.378.400.332.155
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005494
Scope note: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Public MeSH Note: 66
History Note: 66(64)
Entry Version: FOLIC ACID DEFIC
Related: Anemia, Sideroblastic MeSH
FIGLU Test MeSH
DeCS ID: 5631
Unique ID: D005494
NLM Classification: WD 120
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2003/07/09
Folic Acid Deficiency - Preferred
Concept UI M0008663
Scope note A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
Preferred term Folic Acid Deficiency
Entry term(s) Acid Deficiencies, Folic
Acid Deficiency, Folic
Deficiencies, Folic Acid
Deficiency, Folic Acid
Folic Acid Deficiencies



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