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Descriptor English: Mercaptopurine
Descriptor Spanish: Mercaptopurina
Descriptor mercaptopurina
Entry term(s) 1,7-dihidro-6H-purina-6-tiona
6 mercaptopurina
6 tiohipoxantina
6 tiopurina
6-mercaptopurina
6-tiohipoxantina
6-tiopurina
BW 57 323H
BW 57-323H
BW 57323H
leupurina
mercaptopurina Wellcome
mercaptopurina anhidra
monohidrato de 6 mercaptopurina
Scope note: Agente antineoplásico antimetabolito con propiedades inmunosupresoras. Interfiere en la síntiesis de ácidos nucleicos inhibiendo el metabolismo de la purina y se utiliza, generalmente combinado con otros fármacos, en los programas de tratamiento o de mantenimiento de las remisiones de leucemias.
Descriptor Portuguese: Mercaptopurina
Descriptor French: Mercaptopurine
Entry term(s): 6-Mercaptopurine
BW-57-323H
BW57323H
Tree number(s): D02.886.489.534
D03.633.100.759.570
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015122
Scope note: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
Nucleic Acid Synthesis Inhibitors
Registry Number: E7WED276I5
DeCS ID: 8800
Unique ID: D015122
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1985/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/05
Mercaptopurine - Preferred
Concept UI M0023263
Preferred term Mercaptopurine
Entry term(s) 6-Mercaptopurine
BW-57-323H - Narrower
Concept UI M0352354
Preferred term BW-57-323H
Entry term(s) BW57323H



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