DeCS

Descriptor English:

Oxamniquine

Descriptor Spanish:

Oxamniquina

Spanish from Spain

Descriptor	oxamniquina
Scope note:	Antihelmíntico con actividad frente al Schistosoma mansoni, pero no frente a otras Schistosoma spp. La oxamniquina hace que los gusanos emigren desde las venas mesentéricas al hígado, donde son retenidas las formas masculinas; el gusano hembra regresa al mesenterio, pero no puede ya liberar huevos. (Martidale, The Extra Pharmacopoeia, 31st ed, p121).

Descriptor Portuguese:

Oxamniquine

Descriptor French:

Oxamniquine

Tree number(s):

D03.633.100.810.350.600
D03.633.100.810.470.600

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D010073

Scope note:

An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Schistosomicides

Registry Number:

0O977R722D

CAS Type 1 Name:

6-Quinolinemethanol, 1,2,3,4-tetrahydro-2-(((1-methylethyl)amino)methyl)-7-nitro-

DeCS ID:

10249

Unique ID:

D010073

Documents indexed in the Virtual Health Library (VHL):

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