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Descriptor English: Acetoxyacetylaminofluorene
Descriptor Spanish: Acetoxiacetilaminofluoreno
Descriptor acetoxiacetilaminofluoreno
Entry term(s) acetoxiacetamidofluoreno
acetoxifluorenilacetamida
Scope note: Agente alquilante que forma ADDUCTOS DE ADN en la posición C-8 de la GUANINA, con el resultado de roturas en cadenas sencillas. Ha mostrado acción cancerígena.
Descriptor Portuguese: Acetoxiacetilaminofluoreno
Descriptor French: N-Acétoxy-N-fluorén-2-yl-acétamide
Entry term(s): Acetoxyacetamidofluorene
Acetoxyfluorenylacetamide
N Acetoxy 2 acetylaminofluorene
N Acetoxy N acetyl 2 aminofluorene
N-Acetoxy-2-acetylaminofluorene
N-Acetoxy-N-acetyl-2-aminofluorene
Tree number(s): D02.065.064.150.100
D02.241.081.018.110.080.070
D02.455.426.559.847.389.050.060
D04.615.389.050.060
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000099
Scope note: An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Alkylating Agents
Registry Number: 6098-44-8
CAS Type 1 Name: Acetamide, N-(acetyloxy)-N-9H-fluoren-2-yl-
Previous Indexing: Acetamides (1973-1974)
Acetates (1966-1967)
Acetic Acids (1968-1972)
Amides (1966-1972)
Fluorenes (1966-1974)
Public MeSH Note: 91; was see under 2-ACETYLAMINOFLUORENE/analogs & derivatives 1980-90; was see under FLUORENES 1975-79
History Note: 91(75); was see under 2-ACETYLAMINOFLUORENE/analogs & derivatives 1980-90; was see under FLUORENES 1975-79
DeCS ID: 107
Unique ID: D000099
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2012/07/03
Acetoxyacetylaminofluorene - Preferred
Concept UI M0000145
Scope note An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.
Preferred term Acetoxyacetylaminofluorene
Entry term(s) Acetoxyacetamidofluorene
Acetoxyfluorenylacetamide
N Acetoxy 2 acetylaminofluorene
N Acetoxy N acetyl 2 aminofluorene
N-Acetoxy-2-acetylaminofluorene
N-Acetoxy-N-acetyl-2-aminofluorene



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