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Descriptor English: | Phenobarbital | ||||||
Descriptor Spanish: |
Fenobarbital
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Descriptor Portuguese: | Fenobarbital | ||||||
Descriptor French: | Phénobarbital | ||||||
Entry term(s): |
Phénobarbital de sodium Phénobarbital sodique |
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Tree number(s): |
D03.383.742.698.253.650 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D010634 | ||||||
Scope note: | A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. |
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Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
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Pharm Action: |
Anticonvulsants Hypnotics and Sedatives Excitatory Amino Acid Antagonists GABA Modulators Cytochrome P-450 CYP2B6 Inducers Cytochrome P-450 CYP3A Inducers |
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Registry Number: | YQE403BP4D | ||||||
CAS Type 1 Name: | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl- | ||||||
DeCS ID: | 10826 | ||||||
Unique ID: | D010634 | ||||||
NLM Classification: | QV 88 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1966/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2016/05/31 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés hétérocycliques [D03]Composés hétérocycliques
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Phénobarbital
- Preferred
Phénobarbital sodique
- Narrower
Concept UI |
M0016514 |
Preferred term | Phénobarbital |
Concept UI |
M0331275 |
Preferred term | Phénobarbital sodique |
Entry term(s) |
Phénobarbital de sodium |
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