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Descriptor English: Plasminogen
Descriptor Spanish: Plasminógeno
Descriptor plasminógeno
Entry term(s) profibrinolisina
Scope note: Precursor de la plasmina (FIBRINOLISINA). Es una beta-globulina de cadena única, con peso molecular entre 80.000 y 90.000 Da, que se encuentra principalmente asociada al fibrinógeno en el plasma. Los activadores del plasminógeno lo transforman en fibrinolisina. Se utiliza para el desbridamiento de heridas y se ha investigado su utilización como trombolítico.
Descriptor Portuguese: Plasminogênio
Descriptor French: Plasminogène
Entry term(s): 1-Plasminogen, Glutamic Acid
Glu Plasminogen
Glu-Plasminogen
Glutamic Acid 1 Plasminogen
Glutamic Acid 1-Plasminogen
Glutamyl Plasminogen
Plasminogen, Glutamyl
Profibrinolysin
Tree number(s): D08.622.610
D12.776.124.790.223.580
D12.776.377.715.182.580
D12.776.811.243.610
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010958
Scope note: Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Annotation: an enzyme precursor & fibrinolytic agent; /antag: do not confuse with PLASMINOGEN INACTIVATORS which modulate PLASMINOGEN ACTIVATORS, not PLASMINOGEN
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Fibrinolytic Agents
Registry Number: 9001-91-6
CAS Type 1 Name: Plasminogen
Public MeSH Note: 65
History Note: 65(63)
DeCS ID: 11392
Unique ID: D010958
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2009/07/06
Plasminogen - Preferred
Concept UI M0016989
Scope note Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Preferred term Plasminogen
Entry term(s) Profibrinolysin
Glu-Plasminogen - Narrower
Concept UI M0016990
Preferred term Glu-Plasminogen
Entry term(s) 1-Plasminogen, Glutamic Acid
Glu Plasminogen
Glutamic Acid 1 Plasminogen
Glutamic Acid 1-Plasminogen
Glutamyl Plasminogen
Plasminogen, Glutamyl



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