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Descriptor English: | Podophyllotoxin | ||||||
Descriptor Spanish: |
Podofilotoxina
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Descriptor Portuguese: | Podofilotoxina | ||||||
Descriptor French: | Podophyllotoxine | ||||||
Entry term(s): |
Épipodophyllotoxine |
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Tree number(s): |
D02.455.426.559.389.140.450.777 D02.455.426.559.847.638.960.675 D04.615.638.960.675 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011034 | ||||||
Scope note: | A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. |
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Annotation: | /biosyn permitted if by plant |
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Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BI biosynthèse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie GE génétique HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PH physiologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
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Pharm Action: |
Antineoplastic Agents, Phytogenic Keratolytic Agents Tubulin Modulators |
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Registry Number: | L36H50F353 | ||||||
CAS Type 1 Name: | Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))- | ||||||
DeCS ID: | 11464 | ||||||
Unique ID: | D011034 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1973/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2016/07/01 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés polycycliques [D04]Composés polycycliques
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Podophyllotoxine
- Preferred
Épipodophyllotoxine
- Related but not broader or narrower
Concept UI |
M0017087 |
Preferred term | Podophyllotoxine |
Concept UI |
M0017088 |
Preferred term | Épipodophyllotoxine |
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