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Descriptor English: Prednimustine
Descriptor Spanish: Prednimustina
Descriptor prednimustina
Scope note: Ester de CLORAMBUCILO y PREDNISOLONA utilizado como una combinación de agente alquilante y esteroide sintético para tratar diversas leucemias y otras neoplasias. Ocasiona toxicidad gastrointestinal y en la médula ósea.
Descriptor Portuguese: Prednimustina
Descriptor French: Prednimustine
Entry term(s): Leo-1031
Leo1031
NSC-134087
NSC134087
Tree number(s): D02.455.526.728.650.156.700
D04.210.500.745.432.769.795.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011238
Scope note: Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Registry Number: 9403SIO2S8
CAS Type 1 Name: Pregna-1,4-diene-3,20-dione, 21-(4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)-11,17-dihydroxy-, (11beta)-
DeCS ID: 11672
Unique ID: D011238
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1979/05/30
Revision Date: 2017/05/24
Prednimustine - Preferred
Concept UI M0017459
Preferred term Prednimustine
NSC-134087 - Narrower
Concept UI M0351884
Preferred term NSC-134087
Entry term(s) NSC134087
Leo-1031 - Narrower
Concept UI M0351880
Preferred term Leo-1031
Entry term(s) Leo1031



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