| Descriptor English: | Pyrimidine Dimers | ||||||
| Descriptor Spanish: |
Dímeros de Pirimidina
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| Descriptor Portuguese: | Dímeros de Pirimidina | ||||||
| Descriptor French: | Dimères de pyrimidine | ||||||
| Entry term(s): |
Cyclobutane Dimer, Thymine-Thymine Cyclobutane Pyrimidine Dimer Cyclobutane Pyrimidine Dimers Cyclobutane-Pyrimidine Dimer Cyclobutane-Pyrimidine Dimers Cytosine Thymine Dimer Cytosine Thymine Dimers Cytosine-Thymine Dimer Cytosine-Thymine Dimers Dimer, Cyclobutane Pyrimidine Dimer, Cyclobutane-Pyrimidine Dimer, Cytosine-Thymine Dimer, Pyrimidine Dimer, Thymine Dimer, Thymine-Cyclobutane Dimer, Thymine-Thymine Cyclobutane Dimers, Cyclobutane-Pyrimidine Dimers, Cytosine-Thymine Dimers, Pyrimidine Dimers, Thymine Pyrimidine Dimer Pyrimidine Dimer, Cyclobutane Thymine Cyclobutane Dimer Thymine Dimer Thymine Dimers Thymine Thymine Cyclobutane Dimer Thymine-Cyclobutane Dimer Thymine-Thymine Cyclobutane Dimer |
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| Tree number(s): |
D03.383.742.686.600 D13.695.578.424.600 D13.695.740.600 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011740 | ||||||
| Scope note: | Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Previous Indexing: |
Pyrimidine Nucleotides (1974-1976) Thymine Nucleotides (1972-1976) |
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| Public MeSH Note: | 77 |
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| History Note: | 77 |
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| Related: |
DNA Damage
MeSH | ||||||
| DeCS ID: | 12177 | ||||||
| Unique ID: | D011740 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1977/01/01 | ||||||
| Date of Entry: | 1976/04/16 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Pyrimidine Dimers
- Preferred
Thymine-Cyclobutane Dimer
- Related but not broader or narrower
Cytosine-Thymine Dimers
- Narrower
| Concept UI |
M0018256 |
| Scope note | Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION. |
| Preferred term | Pyrimidine Dimers |
| Entry term(s) |
Cyclobutane Pyrimidine Dimer Cyclobutane Pyrimidine Dimers Cyclobutane-Pyrimidine Dimer Cyclobutane-Pyrimidine Dimers Dimer, Cyclobutane Pyrimidine Dimer, Cyclobutane-Pyrimidine Dimer, Pyrimidine Dimers, Cyclobutane-Pyrimidine Dimers, Pyrimidine Pyrimidine Dimer Pyrimidine Dimer, Cyclobutane |
| Concept UI |
M0018257 |
| Preferred term | Thymine-Cyclobutane Dimer |
| Entry term(s) |
Cyclobutane Dimer, Thymine-Thymine Dimer, Thymine Dimer, Thymine-Cyclobutane Dimer, Thymine-Thymine Cyclobutane Dimers, Thymine Thymine Cyclobutane Dimer Thymine Dimer Thymine Dimers Thymine Thymine Cyclobutane Dimer Thymine-Thymine Cyclobutane Dimer |
| Concept UI |
M0018255 |
| Preferred term | Cytosine-Thymine Dimers |
| Entry term(s) |
Cytosine Thymine Dimer Cytosine Thymine Dimers Cytosine-Thymine Dimer Dimer, Cytosine-Thymine Dimers, Cytosine-Thymine |
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