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Descriptor English: Reserpine
Descriptor Spanish: Reserpina
Descriptor reserpina
Scope note: Alcaloide que se encuentra en las raíces de Rauwolfia serpentina y R. vomitoria. La reserpina inhibe la captación de norepinefrina por las vesículas de almacenamiento, lo que resulta en una depleción de catecolaminas y serotonina en las terminaciones de los axones centrales y periféricos. Se ha utilizado como antihipertensivo y antipsicótico y también como herramienta de investigación, pero sus efectos secundarios limitan su uso clínico.
Descriptor Portuguese: Reserpina
Descriptor French: Réserpine
Entry term(s): Raunervil
Raupasil
Rausedil
Rausedyl
Serpasil
Serpivite
V Serp
V-Serp
Tree number(s): D03.132.436.681.933.500
D03.633.100.473.402.681.933.500
D03.633.100.496.500.500.681.933.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012110
Scope note: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
Annotation: reserpine derivatives=RESERPINE /analogs
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Antipsychotic Agents
Adrenergic Uptake Inhibitors
Registry Number: 8B1QWR724A
CAS Type 1 Name: Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
Public MeSH Note: RESERPINE DERIVATIVES was see under RESERPINE 1975-77, was see under YOHIMBANS 1969-74; /adverse effects /poisoning /toxicity were RESERPINE TOXICOLOGY 1963-65
Online Note: use RESERPINE to search RESERPINE DERIVATIVES 1975-77; use YOHIMBANS 1969-74
History Note: RESERPINE DERIVATIVES was see under RESERPINE 1975-77, was see under YOHIMBANS 1969-74; /adv eff-pois-tox was RESERPINE TOXICOLOGY 1963-65
DeCS ID: 12531
Unique ID: D012110
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Reserpine - Preferred
Concept UI M0018861
Scope note An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
Preferred term Reserpine
Rausedil - Narrower
Concept UI M0353123
Preferred term Rausedil
Entry term(s) Rausedyl
Serpasil - Narrower
Concept UI M0353121
Preferred term Serpasil
Raunervil - Narrower
Concept UI M0353125
Preferred term Raunervil
V-Serp - Narrower
Concept UI M0475024
Preferred term V-Serp
Entry term(s) V Serp
Raupasil - Narrower
Concept UI M0353124
Preferred term Raupasil
Serpivite - Narrower
Concept UI M0475023
Preferred term Serpivite



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