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Descriptor English: Ryanodine
Descriptor Spanish: Rianodina
Descriptor rianodina
Scope note: Metil-pirrol carboxilato de RYANIA que desestructura el CANAL DE LIBERACIÓN DE CALCIO DEL RECEPTOR DE RYANODINA para modificar la liberación de CALCIO del RETÍCULO SARCOPLÁSMICO que da lugar a alteración de la CONTRACCIÓN MUSCULAR. Se empleó previamente de modo experimental junto con TAPSIGARGINA y otros inhibidores de la recaptación de la ATPASA DEL CALCIO en el RETÍCULO SARCOPLÁSMICO.
Descriptor Portuguese: Rianodina
Descriptor French: Ryanodine
Tree number(s): D02.455.849.291.686
D03.132.740
D03.383.129.578.805
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012433
Scope note: A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Registry Number: 15662-33-6
CAS Type 1 Name: Ryanodol, 3-(1H-pyrrole-2-carboxylate)
DeCS ID: 12805
Unique ID: D012433
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Ryanodine - Preferred
Concept UI M0019318
Preferred term Ryanodine



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