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Descriptor English: Saxitoxin
Descriptor Spanish: Saxitoxina
Descriptor saxitoxina
Entry term(s) toxina gonyaulaxa
Scope note: Compuesto que contiene un anillo purínico reducido aunque no tiene relación biosintética con los alcaloides purínicos. Es un tóxico que en ocasiones está presente en ciertos moluscos comestibles; es elaborada por GONYAULAX y consumida por moluscos, pescados, etc. sin efectos nocivos. Es neurotóxico y produce PARÁLISIS RESPIRATORIA y otros efectos en los MAMÍFEROS, cuadro que se conoce como intoxicación paralítica por MOLLUSCA.
Descriptor Portuguese: Saxitoxina
Descriptor French: Saxitoxine
Entry term(s): Mytilotoxine
Toxine de Gonyaulax
Tree number(s): D03.633.100.759.794
D20.888.590.662
D23.946.123.257.750
D23.946.580.590.662
D23.946.580.830
D23.946.833.590.662
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012530
Scope note: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Annotation: /antag permitted but consider also ANTITOXINS
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Poisons
Registry Number: 35523-89-8
CAS Type 1 Name: 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS-(3aalpha,4alpha,10aR*))-
DeCS ID: 12912
Unique ID: D012530
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Saxitoxine - Preferred
Concept UI M0019455
Preferred term Saxitoxine
Entry term(s) Mytilotoxine
Toxine de Gonyaulax



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