DeCS

Descriptor English:

Thiouracil

Descriptor Spanish:

Tiouracilo

Spanish from Spain

Descriptor	tiouracilo
Scope note:	Se encuentra en semillas de especies de Brassica y Crucifera. El tiouracilo se ha utilizado como antitiroideo, vasodilatador coronario y en la insuficiencia cardíaca congestiva aunque su uso ha sido ampliamente sustituído por otros fármacos. Se sabe que causa discrasias sanguíneas y se sospecha que sea terato- y carcinogénico.

Descriptor Portuguese:

Tiouracila

Descriptor French:

Thiouracile

Tree number(s):

D03.383.742.698.875.842

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D013889

Scope note:

Occurs in seeds of Brassica and Crucifera species. Thiouracil has been used as antithyroid, coronary vasodilator, and in congestive heart failure although its use has been largely supplanted by other drugs. It is known to cause blood dyscrasias and suspected of terato- and carcinogenesis.

Annotation:

a thyroid antag

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antithyroid Agents
Vasodilator Agents

Registry Number:

59X161SCYL

CAS Type 1 Name:

4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-

DeCS ID:

14274

Unique ID:

D013889

Documents indexed in the Virtual Health Library (VHL):

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