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Descriptor English: Timolol
Descriptor Spanish: Timolol
Descriptor timolol
Entry term(s) L 714,465
L-714,465
L714,465
MK 950
MK-950
MK950
Scope note: Antagonista adrenérgico beta de acción similar al PROPRANOLOL; su isómero levógiro es más activo. El timolol ha sido propuesto como fármaco antihipertensivo, antiarrítmico, antianginoso y antiglaucomatoso. Se utiliza también en el tratamiento de los TRASTORNOS MIGRAÑOSOS y en el temblor.
Descriptor Portuguese: Timolol
Descriptor French: Timolol
Entry term(s): (S)-1-((1,1-Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol
2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (S)-
Blocadren
L 714,465
L-714,465
L714,465
MK 950
MK-950
MK950
Optimol
Timacar
Timolol Hemihydrate
Timolol Maleate
Timolol Maleate, (1:1) Salt
Timoptic
Timoptol
Tree number(s): D02.033.100.624.915
D02.033.755.624.915
D02.092.063.624.915
D02.886.675.867.768
D03.383.129.708.867.768
D03.383.533.640.775
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013999
Scope note: A beta-adrenergic antagonist that is similar in action to PROPRANOLOL; the levo-isomer is more active. Timolol has been proposed as an anti-hypertensive, anti-arrhythmic, anti-angina, and anti-glaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Adrenergic beta-Antagonists
Anti-Arrhythmia Agents
Antihypertensive Agents
Registry Number: 817W3C6175
Previous Indexing: Amino Alcohols (1972-1973)
Morpholines (1972-1975)
Propanolamines (1974-1976)
Thiadiazoles (1972-1976)
Public MeSH Note: 1984; TIMOLOL was indexed under PROPANOLAMINES 1977-1983
History Note: 1984 (1977)
DeCS ID: 14386
Unique ID: D013999
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1976/04/13
Revision Date: 2018/06/19
Timolol - Preferred
Concept UI M0021546
Scope note A beta-adrenergic antagonist that is similar in action to PROPRANOLOL; the levo-isomer is more active. Timolol has been proposed as an anti-hypertensive, anti-arrhythmic, anti-angina, and anti-glaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.
Preferred term Timolol
Timolol Maleate - Narrower
Concept UI M0021551
Preferred term Timolol Maleate
Entry term(s) Timolol Maleate, (1:1) Salt
(S)-1-((1,1-Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol - Narrower
Concept UI M000642429
Preferred term (S)-1-((1,1-Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol
Entry term(s) 2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (S)-
Timoptic - Narrower
Concept UI M0021547
Preferred term Timoptic
Timoptol - Narrower
Concept UI M0021548
Preferred term Timoptol
Timacar - Narrower
Concept UI M0021545
Preferred term Timacar
Timolol Hemihydrate - Narrower
Concept UI M000638570
Preferred term Timolol Hemihydrate
Blocadren - Narrower
Concept UI M0021544
Preferred term Blocadren
L-714,465 - Narrower
Concept UI M0350584
Preferred term L-714,465
Entry term(s) L 714,465
L714,465
MK-950 - Narrower
Concept UI M0021549
Preferred term MK-950
Entry term(s) MK 950
MK950
Optimol - Narrower
Concept UI M0021550
Preferred term Optimol



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