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Descriptor English: | Baclofen | ||||||
Descriptor Spanish: |
Baclofeno
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Descriptor Portuguese: | Baclofeno | ||||||
Descriptor French: | Baclofène | ||||||
Entry term(s): |
Ba-34,647 Ba-34647 Ba34647 PCP-GABA bêta-4-chlorophényl-GABA |
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Tree number(s): |
D02.241.081.114.500.350.100 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D001418 | ||||||
Scope note: | A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. |
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Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
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Pharm Action: |
Muscle Relaxants, Central GABA-B Receptor Agonists |
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Registry Number: | H789N3FKE8 | ||||||
CAS Type 1 Name: | Benzenepropanoic acid, beta-(aminomethyl)-4-chloro- | ||||||
DeCS ID: | 1442 | ||||||
Unique ID: | D001418 | ||||||
NLM Classification: | QV 140 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1980/01/01 | ||||||
Date of Entry: | 1974/11/11 | ||||||
Revision Date: | 2016/07/05 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques
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Baclofène
- Preferred
Ba-34,647
- Narrower
Concept UI |
M0002117 |
Preferred term | Baclofène |
Entry term(s) |
PCP-GABA bêta-4-chlorophényl-GABA |
Concept UI |
M0351459 |
Preferred term | Ba-34,647 |
Entry term(s) |
Ba-34647 Ba34647 |
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